In one form or another, this argument has become popular: Most forms of complementary and alternative medicine (CAM) are just elaborate placebos. However, the placebo effect is incredibly powerful and useful, so these treatments are useful too.Amongst many other people, Michael Brooks from the Guardian makes such a case here. It's an interesting idea. But I don't buy it.
Firstly, to my knowledge, there's no evidence that placebo treatments are clinically effective in the long term. There's no evidence against it, either, but this lack of evidence is important. (I'm not an expert so if such evidence exists, please say so!) There are, certainly, those well-known studies showing that placebos can improve symptoms in the lab, or in short-term clinical trials. And any doctor can tell you that placebos are a useful way of keeping people who want a quick fix satisfied. But is that what we want? Valium is a quick fix for anxiety and insomnia. It works great, in the short term. That doesn't mean you should take it every night. I don't think you should be taking a placebo every night either.
There's something pretty unsettling about the notion of handing out placebos. They're not physiologically addictive, but this doesn't mean that they can't become an expensive and damaging habit. Unlike many people, I'm not especially concerned about the "deception" aspect of it - if deception is what patients need to feel better, then they should get it. What I find unsettling is the idea that we should be medically treating people who we know don't need real medicine.
Prescribing someone any kind of treatment - whether real drugs, sugar pills, CAM, or anything else - legitimizes the notion that they're ill. The idea that one is ill is a very powerful one and you can do someone great harm by leading them to see themselves as ill unnecessarily.
Suppose you have a couple of weeks where you're feeling a bit tired, a bit down, a bit achey, a bit fuzzy. Maybe you're ill - maybe you've got mild anemia, for example. Most likely, though, you're not. Suppose you go to some kind of professional, whether it be your doctor, your homeopath, or anyone else. They might tell you that it's nothing to worry about, it's normal, just get on with your life, and it'll pass. You'd get annoyed, because you'd hoped for a quick fix, but you live with it, and you don't see yourself as suffering from a medical problem, so you don't expect to need treatment. (Could that be the most powerful placebo of all?)
But what if the professional thinks they can treat you? They give you a pill, or a foot rub, or some lovely oil, with confidence and a smile. You expect to get better, and you do. Hooray! Until the next time you start feeling a bit miserable. At which point, you go back to the professional, for more treatment. After all, it worked wonders last time. Again, it works, for a while. Then you start to notice a pain in your back you never did before - could the professional help? Sure. And while you're there, why not see if he has anything to help with that winter cold?
I do not know how often this happens, but it can't be uncommon. Medicalization is not just driven by drug companies. "Complementary and alternative" medicalization is at least as bad; perhaps worse, because drug companies at least have to convince trained doctors to prescribe their drugs. CAM, almost exclusively aimed at consumers, has no such constraints. There is nothing to stop any perfectly healthy person who believes themselves to be ill from going to a homeopath or a nutritionist, and having that belief validated. I would hope that no responsible CAM practioner would ever give a medical diagnosis, but this isn't the point - if you treat someone, even with sugar pills, you are telling them that they are ill.
If the claims of CAM practioners, or indeed CAM-as-placebo supporters, were valid, there probably wouldn't be such demand for CAM. If people really could go to a professional placebo-giver and walk out feeling happy and healthy for ever after, that would be great. Such a person would, presumably, rarely if ever need to see another practitioner, at least for the original ailment (and how many can one person have?) Unfortunately, I don't see this happening very often, although again I'm not aware of any evidence on this point. Saying that most CAM customers are satisfied with their service is not equivalent. The sheer amount of CAM, like the sheer amount of antidepressants being prescribed today, strongly suggests that it is, to an important extent, creating its own market.
[BPSDB]
12 comments:
I have a hunch that the placebo effect is exaggerated when observed in clinical trials. This is rarely important, because generally those trials are testing a treatment against a placebo, but causes problems when it's the placebo effect itself that we want to observe.
I suspect that participating in a trial, which is an altruistic thing to do, is liable to see you receiving a better level of service. Added to that is the "new and shiny" factor - that because the person may or may not be receiving a new treatment, that treatment's effectiveness will be exaggerated. We see this in the way that pain killers become less effective over time - the mechanism and the molecule hasn't change, but the perception of it has.
Unrelatedly, the trouble with many CAM practitioners is that they aren't aware that they're giving out placebos - they have their invented mechanisms, be it water memory, chi channels, quantum information fields, or whatever. They aren't in a position to face the ethical dilemmas of knowingly distributing placebos because as far as they're concerned, they're giving out real treatments.
I attended the Institute for Chinese Medicine in New York City for three years and studied acupuncture. During that time, I would treat family and friends for all kinds of ailments. I got a lot of positive feedback and would get calls time and time again for another treatment for some malady. They believed it was working. Maybe it was a placebo effect, more probably it was the "Tui Na" or 'Chinese backrub' that I would throw in as part of my protocal. I mean, who doesn't love a backrub!, not to mention the treatment was free of charge. I discontinued this practice as I have come to believe that it is all bullshit. There are no 'meridians" of blocked "chi" energy. I could not lie to people, even though the lie would make them feel better in their minds. Great Blog man, i have it bookmarked it and read all the posts. Keep up the good work!
Finally got round to reading this - good post.
I'm not sure I agree with you re: deception of patients (I think that the trend in modern medicine of being open and honest with patients is probably the right course to take). I personally believe that we risk losing more by lying to patients than some might like to admit. For one thing, I'm not sure how patients can maintain trust in their doctors if they are, essentially, being lied to. It also seems to me to be a retrograde step and one that is disempowering (if one accepts that informed consent empowers patients). There's also the issue of whether in prescribing placebos for "non-medical" issues (or "social problems") we are missing a chance to better understand the social problems - but that's dealt with in your argument against medicalization.
I do agree that medicalization is a serious issue - perhaps more serious than the ethical dilemma over prescription of placebos - and it's certainly an interesting one too. I like Ben Goldacre's chapter on medicalization in the Bad Science book - extract here.
He talks of "reframing intelligence, loss of libido, shyness and tiredness as medical pill problems" and considers it to be exploitative as well as disempowering.
Many other excellent points in this post re, e.g., CAM customer surveys and CAM creating its own market (or the point that placebos could become an expensive and damaging habit). I also like the idea that the most powerful placebo of all could be simply telling people who aren't really ill the truth - "it's normal... it'll pass".
Cheers,
jdc.
Heh - I liked that last point too.
It's funny that no-one who believes in the amazing power of the placebo effect ever wonders about the possibility that the very act of giving a placebo could have a powerful, but negative, placebo effect... the reason is that people don't really think about what the "placebo effect" means (that expectations drive behaviour) and just think of placebos as like a silver bullet treatment.
Interesting! I have always been fascinated by the placebo effect and Psycho-neuro-immunology. There is clear evidence that stress weakens the immune system. I have no problem with the placebo as a tool to empower the individual. I do have a problem with science and its view that procedures which work, have a method, are reproducable but are not explained by the scientific dogma must be placebos. Perhaps placebo is the new term for Heresy. A study found that most of the antidepressant medication available had the same efficacy as its placebo control. So who is lying to their patients?
Really enjoying your posts by the way!
Interesting post. One of the arguments made for "good" homeopathy is that the chamges that occur are long term and often permanent. Yes I agree that there are many instances where people are given often repeated medicines. If one truely understands the way to practice then this is clearly contraindicated. Unfortunately there are very few practioners of good homeopathy.
Some of the striking informative tidbits associated with the anti-anxiety medication valium make it apparent that valium is a prescription-based drug for treating anxiety, it belongs to the medicine group termed as benzodiazepines and is duly approved by the FDA (Food and Drugs Administration) for treating anxiety disorders.
I believe there are, in fact, studies that show long-range stability of rehabilitation brought about by placebo treatments. The first that comes to mind is Bruce Moseley's sham arthroscopic surgery trials, where at the time of publication they had tracked patients for 2 years and all sham-surgery receivers were still reporting satisfaction at their recovery (even after being told they'd had sham surgery). There's even a video interview with two of the sham receivers, 6 years after their treatment. One of them, who before "surgery" could barely walk was happily up and about, and the other, who needed a cane to get around, was playing basketball with his grandkids or something remarkable like that.
I'm not sure if there's extensive literature on long-term placebo effects, but here's at least some evidence that they can have a lasting impact.
andrew - Ooh, that is interesting. Thanks. I wasn't aware of that.
Although it still raises the question of whether they would have just got better with the passage of time alone.
I think it's a good point in theory, but I wonder if regression to the mean is a more significant argument made for sickness, infection, and perhaps psychological issues (mild depression, for example). It's really just speculation on my part, but I would tend to think that conditions addressed by surgery, or conditions diagnosed as "chronic" in general, are less likely to fall into the category of "might just get better on their own in time".
It would probably be informative to do a little digging and see if there's any data on the incidence of spontaneous recovery from chronic knee pain (or, better, knee pain that has already been diagnosed as a candidate for arthroscopic surgery). My guess is that this isn't a very common occurrence. But either way, having some background to compare these sham-surgery successes to would be helpful.
I did a bit of Googling just now but didn't come up with anything definitive. Would be interested to hear if you find anything...
People use alternative medicine when they are actually sick too. I'm not a believer in alternative medicine but my parents were, and they used to take us to alternative medicine practitioners when we got sick, unless it was something really really serious (or we needed a note for school).
I truely believe in the placebo effect. The mind has sneaked up on me in so many ways, making me believe something that was all in my head. I do believe in mind over matter, because your mind is powerful, it does wonders good and bad. It is exaggerated sometimes, but shutting out the idea altogether is a little unreasonable.
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